beta-Amanitin, 1MG

SKU:
CAY-18142-1MG
  • $241.00

    • Description

    β-Amanitin

    Technical Information
    Formal Name
    1-L-aspartic acid-α-amanitin
    CAS Number
    21150-22-1
    Molecular Formula
    C39H53N9O15S
    Formula Weight
    920.0
    Purity
    ≥90%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility
    Water: 1 mg/ml
    SMILES
    O=C(N[C@@]1([H])[C@@H](C)[C@@H](O)CO)[C@@]2([H])N(C[C@H](O)C2)C([C@H](CC(O)=O)NC([C@@]([H])(NC(CNC([C@@]([C@H](CC)C)([H])NC(CN3)=O)=O)=O)CS(C4=C(C(C=CC(O)=C5)=C5N4)C[C@@H](C3=O)NC1=O)=O)=O)=O
    InChi Code
    InChI=1S/C39H53N9O15S/c1-4-16(2)31-36(60)41-11-28(53)42-25-15-64(63)38-21(20-6-5-18(50)7-22(20)45-38)9-23(33(57)40-12-29(54)46-31)43-37(61)32(17(3)27(52)14-49)47-35(59)26-8-19(51)13-48(26)39(62)24(10-30(55)56)44-34(25)58/h5-7,16-17,19,23-27,31-32,45,
    InChi Key
    IEQCUEXVAPAFMQ-JAXJKTSHSA-N
    Origin
    Fungi/Amanita phalloides
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years
    Product Description

    β-Amanitin is a cyclic peptide found in several species of the Amanita genus, as well as other poisonous fungi.1 It inhibits RNA polymerase II and III but not RNA polymerase I or bacterial RNA polymerase, thus preventing mammalian protein synthesis.2,3 The biological activity of this toxin is similar to that of α-amanitin (Item No. 17898) but differs structurally by the presence of a carboxyl group, which is useful for coupling reactions.4

    WARNING This product is not for human or veterinary use