Ibotenic acid, 1MG, I2765-1MG

SKU:
I2765-1MG
  • $231.00

    • Description

    Ibotenic acid m ~95%, solid, 1MG

    Synonym(s):
    α-Amino-3-hydroxy-5-isoxazoleacetic acid
    Empirical Formula (Hill Notation):
    C5H6N2O4
    CAS Number:
    2552-55-8
    Molecular Weight:
    158.11
    MDL number:
    MFCD00069294
    PubChem Substance ID:
    24277994
    NACRES:
    NA.32

    assay

    ~95%

    Quality Level

    100

    form

    solid

    color

    white

    solubility

    H2O: 1 mg/mL, clear, colorless (with sonication)
    0.1 M NaOH: 10.7 mg/mL
    0.1 M HCl: 4.7 mg/mL

    SMILES string

    NC(C(O)=O)C1=CC(=O)NO1

    InChI

    1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)

    InChI key

    IRJCBFDCFXCWGO-UHFFFAOYSA-N

    Gene Information

    rat ... Grm1(24414) , Grm2(24415)

    Ibotenic acid has been used as a neurontoxin in rats. It has also been used in inducing a primary permanent lesion monkey cortex M1 neurons.
    Ibotenic acid has been used to perform surgery in adult male zebra finches (Taeniopygia guttata) to study reversing reinforcement-induced vocal changes.

    Packaging

    1, 5, 10, 25 mg in glass bottle

    Biochem/physiol Actions

    Ibotenic acid is an analog of glutamate. It is involved in the excitation of cell bodies and destroys the thalamic reticular nucleus (NRT). It induces high calcium influx leading to neuronal injury. Ibotenic acid is used to induce neurodegeneration due to its excitotoxic functionality.
    Non-selective agonist with preference for NMDA glutamate receptors; neurotoxin; neuroexcitatory amino acid originally isolated from Amanita species.

    Caution

    Hygroscopic

    Signal Word

    Danger

    Hazard Statements

    H301

    Precautionary Statements

    P301 + P310 + P330

    Hazard Classifications

    Acute Tox. 3 Oral

    Storage Class Code

    6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves