Lucidenic Acid A, Item No. 30372, 1mg

SKU:
CAY-30372-1mg
  • $51.00

    • Description

    Lucidenic Acid A

    Item No. 30372

    Technical Information
    Formal Name
    (5α,7β)-7-hydroxy-4,4,14-trimethyl-3,11,15-trioxo-chol-8-en-24-oic acid
    CAS Number
    95311-94-7
    Synonyms
    • Lucideric Acid A
    • Lucidenic Acid α
    Molecular Formula
    C27H38O6
    Formula Weight
    458.6
    Purity
    ≥95%
    Formulation
    A solid
    Solubility
    • Acetonitrile: soluble
    SMILES
    O=C(C[C@]1([H])[C@@H](CCC(O)=O)C)[C@@]([C@]1(C)CC2=O)(C)C3=C2[C@]4(C)[C@](C[C@@H]3O)([H])C(C)(C)C(CC4)=O
    InChi Code
    InChI=1S/C27H38O6/c1-14(7-8-21(32)33)15-11-20(31)27(6)23-16(28)12-18-24(2,3)19(30)9-10-25(18,4)22(23)17(29)13-26(15,27)5/h14-16,18,28H,7-13H2,1-6H3,(H,32,33)/t14-,15-,16+,18+,25+,26-,27+/m1/s1
    InChi Key
    INIPQDKLXQHEAJ-NCQSLMINSA-N
    Origin
    Fungi/Ganoderma
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years
    Product Description

    Lucidenic acid A is a triterpene originally isolated from G. lucidum and has anticancer activity.1,2 It is cytotoxic to HepG2, HepG2 2.2.15', and P388 cancer cells (IC50s = 0.164, 0.205, and 17 nM, respectively). Lucidenic acid A inhibits increases in matrix metalloproteinase-2 (MMP-2) and MMP-9 activity and Matrigel™ invasion induced by phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in HepG2 cells.2

    WARNING This product is not for human or veterinary use.