Ochratoxin B, 1MG

SKU:
CAY-16167-1MG
  • $210.00

    • Description

    Ochratoxin B, 1MG

    Item No. 16167

    Technical Information
    Formal Name
    N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine
    CAS Number
    4825-86-9
    Synonyms
    • OTB
    Molecular Formula
    C20H19NO6
    Formula Weight
    369.4
    Purity
    ≥98%
    Formulation
    A crystalline solid
    Solubility
    • DMF: 10 mg/ml
    • DMSO: 15 mg/ml
    • Ethanol: 50 mg/ml
    • Ethanol:PBS (pH 7.2) (1:1): 0.50 mg/ml
    λmax
    218, 319 nm
    SMILES
    O=C1O[C@@H](C)CC2=C1C(O)=C(C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)C=C2
    InChi Code
    InChI=1S/C20H19NO6/c1-11-9-13-7-8-14(17(22)16(13)20(26)27-11)18(23)21-15(19(24)25)10-12-5-3-2-4-6-12/h2-8,11,15,22H,9-10H2,1H3,(H,21,23)(H,24,25)/t11-,15-/m0/s1
    InChi Key
    DAEYIVCTQUFNTM-NHYWBVRUSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years
    Product Description

    Ochratoxins are mycotoxins produced by Aspergillus and Penicillium species of fungi that contaminate foods.1,2 Ochratoxin A (OTA, Item No. 11439) is a chlorinated form with toxicity that targets the kidneys, causing nephropathy and renal adenomas.1,2 OTB is a non-chlorinated analog of OTA that has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion.3,4,5 OTB inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 µg/ml but lacks the genotoxic activity of OTA, even at higher concentrations.3

    WARNING This product is not for human or veterinary use.