Bradykinin Fragment 1-7, (HPLC), 1MG

SKU:
B1651-1MG
  • $84.40

    • Description

    Bradykinin Fragment 1-7, ≥97% (HPLC), 1MG

    Synonym(s):
    1-7-Bradykinin
    Empirical Formula (Hill Notation):
    C35H52N10O9
    CAS Number:
    23815-87-4
    Molecular Weight:
    756.85
    MDL number:
    MFCD00076262
    PubChem Substance ID:
    24891606
    NACRES:
    NA.26

    PROPERTIES

    Quality Level

    200

    assay

    ≥97% (HPLC)

    form

    powder

    color

    white

    UniProt accession no.

    P01161

    storage temp.

    −20°C

    SMILES string

    NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(CO)C(=O)N4CCCC4C(O)=O

    InChI

    1S/C35H52N10O9/c36-22(10-4-14-39-35(37)38)31(50)44-16-6-12-26(44)33(52)43-15-5-11-25(43)30(49)40-19-28(47)41-23(18-21-8-2-1-3-9-21)29(48)42-24(20-46)32(51)45-17-7-13-27(45)34(53)54/h1-3,8-9,22-27,46H,4-7,10-20,36H2,(H,40,49)(H,41,47)(H,42,48)(H,53,54)(H4,37,38,39)

    InChI key

    CRROPKNGCGVIOG-UHFFFAOYSA-N

    Gene Information

    rat ... Nppa(24602)

    Amino Acid Sequence

    Arg-Pro-Pro-Gly-Phe-Ser-Pro

    General description

    Bradykinin fragment 1-7 (BK-(1-7)), an endogenous peptide, is present in plasma.[1]

    Application

    Bradykinin Fragment 1-7 has been used as an external calibrant/standard in the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis of protein spots.[2][3]
    Bradykinin Fragment 1-7 is used in research on the specificity and kinetics of kininase(s).

    Biochem/physiol Actions

    Bradykinin (BK) is a pro-inflammatory mediator and a neuromediator. It modulates several vascular and renal functions. Bradykinin (BK) plays a key role in inducing vascular permeability and mitogenesis. It helps to activate the liberation of nitric oxide in inflammatory and cancer tissues.[4]

    SAFETY INFORMATION

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves