Ganoderol B, Item No. 34324, 1mg

SKU:
CAY-34324-1mg
$81.00

Description

Ganoderol B

Item No. 34324

Technical Information
Formal Name
lanosta-7,9(11),24E-triene-3β,26-diol
CAS Number
104700-96-1
Synonyms
  • Ganodermadiol
  • (+)-Ganoderol B
Molecular Formula
C30H48O2
Formula Weight
440.7
Purity
≥95%
Formulation
A solid
Solubility
  • DMSO: soluble
SMILES
C[C@]12C3=CC[C@](C(C)([C@H](CC4)O)C)([H])[C@@]4(C)C3=CC[C@@]1([C@]([C@@H](CC/C=C(C)/CO)C)([H])CC2)C
InChi Code
InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1
InChi Key
AOXXVRDKZLRGTJ-AZIDVCJLSA-N
Origin
Fungi/Ganoderma lucidum
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
Product Description

Ganoderol B is a triterpenoid that has been found in G. lucidum and has diverse biological activities.1,2,3,4,5 It inhibits angiotensin-converting enzyme (ACE) and α-glucosidase (IC50s = 220 and 119.8 µM, respectively).1,2 Ganoderol B is cytotoxic to HGC-27 gastric, HeLa cervical, and A549 lung cancer cells (IC50s = 16.15, 12.64, and 9.77 µM, respectively).3 It prevents herpes simplex virus 1 (HSV-1) infection in Vero cells (EC50 = 68 µM).4 Ganoderol B (0.001 and 0.1 mg/kg) reduces testosterone-induced increases in ventral prostate weight in castrated rats.5

WARNING This product is not for human or veterinary use.