Arachidonic acid, 50MG

SKU:
23401-50MG
  • $215.00

    • Description

    Arachidonic acid, 50MG

    analytical standard

    Synonym(s):
    Immunocytophyte, Eicosa-5Z,8Z,11Z,14Z-tetraenoic acid, cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic acid
    Linear Formula:
    CH3(CH2)4(CH=CHCH2)4CH2CH2CO2H
    CAS Number:
    506-32-1
    Molecular Weight:
    304.47
    Beilstein:
    1713889
    EC Number:
    208-033-4
    MDL number:
    MFCD00004417
    PubChem Substance ID:
    329752420
    NACRES:
    NA.24

    PROPERTIES

    Quality Level

    100

    biological source

    synthetic

    grade

    analytical standard

    assay

    ≥97.0% (GC)

    form

    liquid

    shelf life

    limited shelf life, expiry date on the label

    refractive index

    n20/D 1.4872 (lit.)

    bp

    169-171 °C/0.15 mmHg (lit.)

    mp

    −49 °C (lit.)

    density

    0.922 g/mL at 25 °C (lit.)

    application(s)

    food and beverages

    format

    neat

    functional group

    carboxylic acid

    storage temp.

    2-8°C

    SMILES string

    OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O

    InChI

    1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-

    InChI key

    YZXBAPSDXZZRGB-DOFZRALJSA-N

    DESCRIPTION

    Biochem/physiol Actions

    Arachidonic acid stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules (collagen IV and vitronectin) .
    Arachidonic acid (AA) is an unsaturated ω6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via cytochrome p450-catalyzed metabolism. AA and its metabolites play important roles in a variety of biological processes, including signal transduction, smooth muscle contraction, chemotaxis, cell proliferation and differentiation, and apoptosis. AA has been demonstrated to bind to the a subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane.

    SAFETY INFORMATION

    Storage Class Code

    10 - Combustible liquids

    WGK

    WGK 3

    Flash Point(F)

    235.4 °F - closed cup

    Flash Point(C)

    113 °C - closed cup