Thiamine pyrophosphate, 25G

SKU:
C8754-25G
$300.00

Description

Thiamine pyrophosphate ≥95%, 25G

Synonym: Aneurinepyrophosphoric acid, Cocarboxylase, Thiamine pyrophosphate chloride

  • CAS Number 154-87-0

     

  • Empirical Formula (Hill Notation) C12H19ClN4O7P2S

     

  • Molecular Weight 460.77

     

  •  Beilstein/REAXYS Number 3875902

     

  •  EC Number 205-836-1

     

  •  MDL number MFCD00038740

     

  •  PubChem Substance ID 24893100

     

  •  NACRES NA.54

Safety Information

Personal Protective Equipment 
Eyeshields, Gloves, type N95 (US)
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Application

Thiamine pyrophosphate from Sigma has been used as a substrate to assay the enzymes in golgi lamellae isolated from rat tissue.[1]

Thiamine pyrophosphate has been used:
• for the preparation of chitosan nano-particles[3]
• as a standard for vitamin B1 and its derivative in high-performance
• liquid chromatography (HPLC) analysis[4]
• immunofluorescence[5]

Packaging

1, 5, 25, 100 g in poly bottle

Biochem/physiol Actions

Thiamine pyrophosphate (TPP) is a coenzyme of transketolase, that catalyzes the cleavage of ribulose-5-phosphate. This reaction leads to the formation of D-glyceraldehyde-3-phosphate. It requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. TPP is capable of decarboxylating hydroxypyruvate in the presence of an ′acceptor aldehyde′.[2]