Propiconazole-d7, 1MG

SKU:
CAY-31177-1MG
  • $396.00

    • Description

    Propiconazole-d7

    Propiconazole-d7 is intended for use as an internal standard for the quantification of propiconazole (Item No. 18853) by GC- or LC-MS. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption.1 It inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s = 0.04 and >200 µM, respectively).2 Propiconazole inhibits the growth of T. deformans and R. stolonifer (EC50s = 0.073 and 4.6 µg/ml, respectively), as well as A. niger, M. fructigena, S. nodorum, T. harzanium, R. solani, and S. rolfsii at concentrations ranging from 0.1 to 5 ppm.3 It increases the weight of seminal vesicles and vas deferens, as well as the percentage of sperm with abnormal tail morphology, and decreases the plasma concentration of estradiol in male rats when administered at a dose of 4 mg/kg.4 Propiconazole increases production of reactive oxygen species (ROS), the number of DNA mutations, and the incidence of tumor formation in mouse liver.5 Formulations containing propiconazole have been used in the control of fungi in agriculture.

    WARNING This product is not for human or veterinary use.

    This product is sold exclusively for research and analytical uses. It is formulated and packaged for use in controlled laboratory settings. Bulk sizes are not available for purchase.

    Technical Information
    Formal Name
    1-((2-(2,4-dichlorophenyl)-4-(propyl-d7)-1,3-dioxolan-2-yl)methyl)-1H-1,2,4-triazole
    CAS Number
    1246818-14-3
    Molecular Formula
    C15H10Cl2D7N3O2
    Formula Weight
    349.3
    Purity
    ≥99% deuterated forms (d1-d7)
    Formulation(Request formulation change)
    An oil
    Solubility
    • Chloroform: slightly soluble
    • Methanol: slightly soluble
    SMILES
    ClC1=CC=C(C2(CN3C=NC=N3)OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])CO2)C(Cl)=C1
    InChi Code
    InChI=1S/C15H17Cl2N3O2/c1-2-3-12-7-21-15(22-12,8-20-10-18-9-19-20)13-5-4-11(16)6-14(13)17/h4-6,9-10,12H,2-3,7-8H2,1H3/i1D3,2D2,3D2
    InChi Key
    STJLVHWMYQXCPB-NCKGIQLSSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years