Periodic acid, for synthesis, 500g

SKU:
8222880500
  • $426.00

    • Description

    Periodic acid, for synthesis, >98% 500g

    Synonym(s):
    Periodic acid
    Empirical Formula (Hill Notation):
    H5IO6
    CAS Number:
    10450-60-9
    Molecular Weight:
    227.94
    MDL number:
    MFCD00011344
    EC Index Number:
    233-937-0

    PROPERTIES

    Quality Level

    200

    assay

    ≥98% (iodometric)

    form

    solid

    reaction suitability

    reagent type: oxidant

    pH

    1.2 (20 °C, 100 g/L in H2O)

    mp

    122 °C

    solubility

    ethanol: soluble at 20 °C
    water: soluble at 20 °C

    bulk density

    1400 kg/m3

    storage temp.

    15-25°C

    InChI

    1S/H5IO6/c2-1(3,4,5,6)7/h(H5,2,3,4,5,6,7)

    InChI key

    TWLXDPFBEPBAQB-UHFFFAOYSA-N

    DESCRIPTION

    Application

    Periodic acid can be used as a reagent for the oxidative cleavage of 1,2 diols to ketones or aldehydes, and epoxides to aldehydes. It is also used in the oxidative cleavage of various protecting groups such as acetonide, tetrahydropyranyl ether (THP), ethoxyethyl acetals, cyclic acetals, dithioacetals, and oxathioacetals.
    It can also be used:
    • In the selective N-nitrosation of secondary amines in the presence of sodium nitrite, and wet silica gel.
    • As a stoichiometric oxidant with chromium (IV) acetate for the oxidation of tertiary C−H bonds to tertiary alcohols.
    • In combination with chromium oxide to oxidize primary alcohols to carboxylic acids; alkylbenzenes to benzoic acids; and cyclic benzyl ethers to the corresponding lactones.
    • In the iodination of bulky polyalkyl benzenes in the presence of iodine.
    • In the oxidative coupling of polycyclic aromatic hydrocarbons in the presence of aqueous acetic acid.
    • In the selective oxidation of sulfides to sulfoxides using FeCl3 as a catalyst.

    Analysis Note

    Assay (iodometric): ≥ 98.0 %
    Melting range (lower value): ≥ 124 °C
    Melting range (upper value): ≤ 129 °C

    SAFETY INFORMATION

    Signal Word

    Danger

    Hazard Statements

    H271 - H314 - H372 - H400

    Precautionary Statements

    P210 - P260 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338

    Hazard Classifications

    Aquatic Acute 1 - Eye Dam. 1 - Ox. Sol. 1 - Skin Corr. 1B - STOT RE 1 Oral

    Target Organs

    Thyroid

    Storage Class Code

    5.1A - Strongly oxidizing hazardous materials

    WGK

    WGK 3