p-Anisidine, 5G

SKU:
A88255-5G
  • $22.80

    • Description

    p-Anisidine, 99%, 5G

    Synonym(s):
    4-Aminoanisole, 4-Methoxyaniline
    Linear Formula:
    CH3OC6H4NH2
    CAS Number:
    104-94-9
    Molecular Weight:
    123.15
    Beilstein:
    471556
    MDL number:
    MFCD00007864
    PubChem Substance ID:
    24891372
    NACRES:
    NA.22

    PROPERTIES

    Quality Level

    200

    Assay

    99%

    form

    solid

    autoignition temp.

    959 °F

    bp

    240-243 °C (lit.)

    mp

    56-59 °C (lit.)

    SMILES string

    COc1ccc(N)cc1

    InChI

    1S/C7H9NO/c1-9-7-4-2-6(8)3-5-7/h2-5H,8H2,1H3

    InChI key

    BHAAPTBBJKJZER-UHFFFAOYSA-N

    Application

    p-Anisidine can undergo aerobic oxidation in the presence of gold catalysts to form aromatic azo compounds.[1]
    p-Anisidine can be used:
    • In the diastereoselective and enantioselective synthesis of CF3-substituted azoridines catalyzed by a chiral Bronsted acid.[2]
    • To prepare 4-organoselenium-quinolines through multi-component Povarov reaction with ethyl glyoxylate and ethynyl(phenyl)selane, catalyzed by Yb(OTf)3.[3]
    • As a starting material to synthesize 3-fluoro-6-methoxyquinoline in two steps.[4],
    • To prepare N-PMP protected α-aminopropargylphosphonates by reacting with terminal alkynes and diethyl formylphosphonate hydrate using silver(I) triflate as a catalyst.[5]

    SAFETY INFORMATION

    Signal Word

    Danger

    Hazard Statements

    H300 + H310 + H330 - H350 - H373 - H400

    Precautionary Statements

    P202 - P260 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310

    Hazard Classifications

    Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Carc. 1B - STOT RE 2

    Storage Class Code

    6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

    WGK

    WGK 3

    Flash Point(F)

    251.6 °F - closed cup

    Flash Point(C)

    122 °C - closed cup