Description
01423 Sigma-Aldrich
N-Acetyl-D-penicillamine
for HPLC derivatization, ≥99.0% (T)
Synonym: N-Acetyl-3-mercapto-D-valine, NAP, NAPA
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CAS Number 15537-71-0
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Empirical Formula (Hill Notation) C7H13NO3S
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Molecular Weight 191.25
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Beilstein Registry Number 1724742
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EC Number 239-585-4
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MDL number MFCD00078887
Description
Application
Chiral reagent for the precolumn derivatization of amino acids or amino alcohols; the diastereoisomers formed can be efficiently resolved by HPLC on conventional reversed-phase columns[1]
Biochem/physiol Actions
N-Acetyl-D-penicillamine (NAP or NAPA), a thiol compound, is often used as a control molecule in studies involving nitric oxide donor molecules such as S-nitroso-N-acetyl-dl-penicillamine (SNAP) and sodium nitroprusside (SNP). N-acetyl-D-penicillamine (NAPA) is also used as a heavy metal chelator.
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Properties
| Related Categories | A - H, Amino Acids, Analytical Reagents,Analytical/Chromatography, Biochemicals and Reagents, More... |
| grade | for HPLC derivatization |
| InChI Key | MNNBCKASUFBXCO-YFKPBYRVSA-N |
| assay | ≥99.0% (T) |
| optical activity | [α]20/D +10±2°, c = 1% in ethanol |
| mp | 185-190 °C (dec.)a |
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