Menthol, 5G

SKU:
M2772-5G-A
  • $48.60

    • Description

    Menthol, 99%, 5G

    PROPERTIES

    vapor pressure

    0.8 mmHg ( 20 °C)

    Quality Level

    200

    Assay

    99%

    bp

    216 °C (lit.)

    mp

    34-36 °C (lit.)

    density

    0.89 g/mL at 25 °C (lit.)

    application(s)

    metabolomics
    vitamins, nutraceuticals, and natural products

    SMILES string

    CC(C)C1CCC(C)CC1O

    InChI

    1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3

    InChI key

    NOOLISFMXDJSKH-UHFFFAOYSA-N

    Gene Information

    human ... TRPA1(8989) , TRPM8(79054)

    General description

    Menthol (C10H20O) is a terpenoid compound. It is extracted from the plants belonging to Mentha genus in the Lamiaceae family.[1]
    Menthol is a cyclic monoterpene alcohol, which is extracted from essential oils of Mentha canadensis and Mentha x piperita. It possesses antimicrobial, anticancer and anti-inflammatory properties.[2] Menthol acts as a transient receptor potential cation channel (TRPM8) agonist.[3] It also exhibits analgesic, antipruritic, anesthetic and cooling effects.[2]

    Application

    Menthol has been used:
    • to test its antifungal susceptibility[4]
    • to determine its efficacy as an anesthetic in fish[5]
    • to activate transient receptor potential cation channel (TRPM8)[6][7]
    • as an odorant for measuring sniffing dynamics[8]

    Biochem/physiol Actions

    Menthol exhibits antifungal action on the membrane permeability and the cell wall consistency, this might leads to cell death or inhibition of the C. albicans filamentation. Therefore, it can be used as a potential therapeutic agent for candidiasis.[1] In addition to antifungal activity, menthol also exhibits anesthetic, antispasmodic, anti-ulcer and antiviral properties. It is considered as a safe compound for animal life. Therefore, Menthol is widely used in pharmaceuticals, cosmetics and food industries.[5]

    SAFETY INFORMATION

    Pictograms

    GHS07

    Signal Word

    Warning

    Hazard Statements

    H315 - H319

    Precautionary Statements

    P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

    Hazard Classifications

    Eye Irrit. 2 - Skin Irrit. 2

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 1

    Flash Point(F)

    204.8 °F

    Flash Point(C)

    96 °C

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves