L-Thyroxine (T4) solution 100 ug/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant

SKU:
T-073-1ML
  • $92.00

    • Description

    L-Thyroxine (T4) solution 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant

    Synonym(s):
    3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine, L-Thyroxine, 3,3′,5,5″-Tetraiodo-L-thyronine, T4
    Linear Formula:
    HOC6H2(I)2OC6H2(I)2CH2CH(NH2)CO2H
    CAS Number:
    51-48-9
    Molecular Weight:
    776.87
    Beilstein/REAXYS Number:
    2228515
    MDL number:
    MFCD00002595
    PubChem Substance ID:
    329826617
    NACRES:
    NA.24

    Quality Level

    300

    grade

    certified reference material

    feature

    Snap-N-Spike®/Snap-N-Shoot®

    packaging

    ampule of 1 mL

    manufacturer/tradename

    Cerilliant®

    concentration

    100 μg/mL in methanol with 0.1N NH3

    mp

    223 °C (dec.) (lit.)

    Featured Industry

    Forensics and Toxicology

    format

    single component solution

    storage temp.

    −20°C

    SMILES string

    N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O

    InChI

    1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1

    InChI key

    XUIIKFGFIJCVMT-LBPRGKRZSA-N

    Gene Information

    human ... THRA(7067) , THRB(7068)

    Thyroxine or T4 is a thyroid hormone responsible for regulation of the body′s basal metabolic rate and essential for growth, development and heart and nervous system function. Free and total T4 serum levels are measured by LC-MS/MS for determination of hyper- or hypothyroidism as well as for monitoring treatment with synthetic thyroid hormones. This Certified Spiking Solution® is suitable for use in LC-MS/MS testing methods as starting materials in preparation of linearity standards, calibrators, and controls.

    Biochem/physiol Actions

    L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis.

    Legal Information

    CERILLIANT is a registered trademark of Cerilliant Corporation
    CERTIFIED SPIKING SOLUTIONS is a registered trademark of Cerilliant Corporation
    Snap-N-Shoot is a registered trademark of Cerilliant Corporation
    Snap-N-Spike is a registered trademark of Cerilliant Corporation

    Pictograms

    GHS02,GHS06,GHS08

    Signal Word

    Danger

    Hazard Statements

    H225 - H301 + H311 + H331 - H370

    Precautionary Statements

    P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311

    Target Organs

    Eyes

    RIDADR

    UN1230 - class 3 - PG 2 - Methanol, solution

    WGK Germany

    WGK 1

    Flash Point(F)

    49.5 °F - closed cup

    Flash Point(C)

    9.7 °C - closed cup