L-Ascorbic acid, 100MG

SKU:
A4403-100MG
  • $80.30

    • Description

    L-Ascorbic acid

    powder, suitable for cell culture, γ-irradiated

    Synonym(s):
    L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
    Empirical Formula (Hill Notation):
    C6H8O6
    CAS Number:
    50-81-7
    Molecular Weight:
    176.12
    Beilstein:
    84272
    EC Number:
    200-066-2
    MDL number:
    MFCD00064328
    PubChem Substance ID:
    24890857
    NACRES:
    NA.75

    PROPERTIES

    biological source

    synthetic (organic)

    Quality Level

    200

    sterility

    γ-irradiated

    form

    powder

    mol wt

    Mw 176.12 g/mol

    technique(s)

    cell culture | insect: suitable
    cell culture | mammalian: suitable
    cell culture | plant: suitable

    color

    white to off-white

    pH

    1.0-2.5 (25 °C, 176 g/L in water)

    mp

    190-194 °C (dec.)

    solubility

    H2O: 10 mg/mL

    SMILES string

    OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

    InChI

    1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

    InChI key

    CIWBSHSKHKDKBQ-JLAZNSOCSA-N

    Gene Information

    human ... SLC23A2(9962)

    General description

    L-ascorbic acid is an unsaturated γ-lactone ring containing an enediol configuration (–COH=COH) attached with a carbonyl group.[1]

    Application

    For use in cell culture applications as an antioxidant and to regenerate tocopherol.
    L-ascorbic acid has been used:
    • in an osteogenic supplement for the growth of cells[2]
    • as a component in the differentiation media[3]
    • in WS-MSCs (Werner syndrome-mesenchymal stem cells) to study rescuing properties of ascorbic acid on aging defects[4]

    Packaging

    100 mg

    Biochem/physiol Actions

    L-ascorbic acid mainly exhibits antioxidant properties. It protects plants from oxidative stress and mammals from diseases associated with oxidative stress.[5] L-ascorbic acid mainly protects from hydroxyl radicals, superoxide and singlet oxygen. In addition, it also reduces the membrane-linked antioxidant α-tocopherol (oxidised form).[6] L-Ascorbic acid enhances endothelium-dependent vasodilation in various disorders, including diabetes, coronary artery disease, hypertension and chronic heart failure.[1]

    SAFETY INFORMATION

    Storage Class Code

    13 - Non Combustible Solids

    WGK

    WGK 1

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves