Imidacloprid-d₄

Imidacloprid-d₄ is intended for use as an internal standard for the quantification of imidacloprid (Item No. 24130) by GC- or LC-MS. Imidacloprid is a broad-spectrum neonicotinoid insecticide that is effective against sucking and biting insects and insects of the Coleopteran and Lepidoptera orders.^1,2 It is an agonist of insect acetylcholine receptors (nAChRs) with K_i values of 1.9, 2.1, 290, and 50 nM for M. persicae and D. melanogaster receptors, rat brain membranes, and rat recombinant receptors containing α4β2 subunits, respectively.^3,4 Imidacloprid is lethal to M. persicae with LD₉₅ values of approximately 2 and 160 pg/aphid via oral and topical administration, respectively.² It impairs aversive learning and memory retention in honey bees following chronic sublethal exposure of 20.8 ppb.⁵ In a mouse model of high-fat diet-induced obesity, imidacloprid (0.06-6 mg/kg per day) increases body weight gain and adiposity and impairs glucose metabolism without increasing total food intake.⁶ Formulations containing imidacloprid have been used as insecticides in residential, veterinary, and agricultural settings.

WARNING This product is not for human or veterinary use.

This product is sold exclusively for research and analytical uses. It is formulated and packaged for use in controlled laboratory settings. Bulk sizes are not available for purchase.