Fisetin, 100mg

SKU:
CAY-15246-100MG
  • $32.00

    • Description

    Product Description

    Fisetin is a flavonoid that has been found in various fruits and vegetables and has diverse biological activities. It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay and inhibits oxidative burst induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP) in isolated human polymorphonuclear neutrophils (PMNs) when used at a concentration of 10 µM. Fisetin (10-60 µM) induces cell cycle arrest at the G1 phase and apoptosis in, as well as inhibits the proliferation of, LNCaP prostate cancer cells. It inhibits LPS-induced production of nitrite, prostaglandin E2 (PGE2), and NF-κB activation in RAW 264.7 cells. Fisetin (1 mg/animal) reduces tumor growth in a CWR22Rυ1 prostate cancer mouse xenograft model.

    WARNING This product is not for human or veterinary use.

    Technical Information
    Formal Name
    2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
    CAS Number
    528-48-3
    Synonyms
    • CI-75620
    • NSC 407010
    • NSC 656275
    Molecular Formula
    C15H10O6
    Formula Weight
    286.2
    Purity
    ≥90%
    Formulation
    A crystalline solid
    Solubility
    • DMF: 30 mg/ml
    • DMSO: 30 mg/ml
    • DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
    • Ethanol: 5 mg/ml
    λmax
    250, 320, 364 nm
    SMILES
    O=C1C2=C(C=C(O)C=C2)OC(C3=CC=C(O)C(O)=C3)=C1O
    InChi Code
    InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
    InChi Key
    XHEFDIBZLJXQHF-UHFFFAOYSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years