Diquat-d12 (bromide), 1MG

SKU:
CAY-26778-1MG
  • $62.00

    • Description

    Diquat-d12 (bromide)

    Diquat-d12 is intended for use as an internal standard for the quantification of diquat (Item No. 26251) by GC- or LC-MS. Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).1 Diquat administration has been used to induce oxidative stress in vitro and in animal models.2,3,4 It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg.2 Formulations containing diquat have been used in agriculture for crop desiccation and defoliation.

    WARNING This product is not for human or veterinary use.

    This product is sold exclusively for research and analytical uses. It is formulated and packaged for use in controlled laboratory settings. Bulk sizes are not available for purchase.

    Technical Information
    Formal Name
    6,7-dihydrodipyrido[1,2-a:2',1'-c]pyrazine-5,8-diium-1,2,3,4,6,6,7,7,9,10,11,12-d12, dibromide
    Molecular Formula
    C12D12N2 • 2Br
    Formula Weight
    356.1
    Purity
    ≥99% deuterated forms (d1-d12)
    Formulation(Request formulation change)
    A solid
    Solubility
    • DMSO: 1 mg/ml
    • Ethanol: slightly soluble
    SMILES
    [2H]C1([2H])[N+]2=C([2H])C([2H])=C([2H])C([2H])=C2C3=[N+](C([2H])=C([2H])C([2H])=C3[2H])C1([2H])[2H].[Br-].[Br-]
    InChi Code
    InChI=1S/C12H12N2.2BrH/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1;;/h1-8H,9-10H2;2*1H/q+2;;/p-2/i1D,2D,3D,4D,5D,6D,7D,8D,9D2,10D2;;
    InChi Key
    ODPOAESBSUKMHD-ZJDAYHFVSA-L
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years