Desalkylflurazepam (CRM), 1MG

SKU:
CAY-19698-1MG
  • $32.00

    • Description

    Desalkylflurazepam (CRM)

    Desalkylflurazepam (CRM) (Item No.19698) is an analytical reference material that is structurally categorized as a benzodiazepine. It is an active metabolite of several benzodiazepines, including flurazepam (Item No. 18160), flutoprazepam, fludiazepam, midazolam (Item Nos. 19391 | 16193), and quazepam. Desalkylflurazepam inhibits L-type voltage-gated calcium channels (Cav; IC50s = 55 and 37 µM for Cav1.2 and 1.3, respectively) by positively modulating GABAA receptors.1 It can be detected in urine, serum, and meconium by LC-MS/MS.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    Synonyms
    • N-Desalkylflurazepam
    • N-Desalkyl-2-oxoquazepam
    • nor-Flurazepam
    • Norfludiazepam
    • Ro 5-3367
    Technical Information
    Formal Name
    7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
    CAS Number
    2886-65-9
    Molecular Formula
    C15H10ClFN2O
    Formula Weight
    288.7
    Formulation(Request formulation change)
    A 1 mg/ml solution in methanol
    SMILES
    ClC(C=C1)=CC2=C1NC(CN=C2C3=CC=CC=C3F)=O
    InChi Code
    InChI=1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
    InChi Key
    UVCOILFBWYKHHB-UHFFFAOYSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Wet ice in continental US; may vary elsewhere
    Stability
    ≥ 2 years