Cotinine, 50MG

SKU:
CAY-15314-50MG
  • $57.00

    • Description

    (−)-Cotinine

    Item No. 15314

    Technical Information
    Formal Name
    1-methyl-5S-(3-pyridinyl)-2-pyrrolidinone
    CAS Number
    486-56-6
    Synonyms
    • NIH 10498
    Molecular Formula
    C10H12N2O
    Formula Weight
    176.2
    Purity
    ≥98%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility(Learn about Variance in Solubility)
    • DMF: 30 mg/ml
    • DMSO: 30 mg/ml
    • Ethanol: 30 mg/ml
    • PBS (pH 7.2): 10 mg/ml
    λmax
    262 nm
    SMILES
    O=C1CC[C@@H](C2=CN=CC=C2)N1C
    InChi Code
    InChI=1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1
    InChi Key
    UIKROCXWUNQSPJ-VIFPVBQESA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years
    Product Description

    Cotinine is a minor alkaloid found in tobacco plants and is a major metabolite of nicotine.1 It has a long pharmacological half-life (15-19 hours) compared to that of nicotine (2-3 hours) and is often used as a biomarker to detect tobacco use.2,3,4 Cotinine binds nicotinic- and muscarinic-type acetylcholine receptors with minimal receptor desensitization and demonstrates antipsychotic drug-like properties in behavioral models, neuroprotective properties in neurodegenerative disease models, and enhances attention in a delayed matching-to-sample task.2

    WARNING This product is not for human or veterinary use.