Clomipramine (hydrochloride), 1MG

SKU:
CAY-15884-1G
  • $37.00

    • Description

    Clomipramine (hydrochloride)

    Clomipramine is a tricyclic antidepressant, the 3-chlorinated derivative of imipramine (Item No. 15890).1 Like imipramine, clomipramine potently inhibits serotonin and norepinephrine reuptake (Kis = 7.4 and 96 nM, respectively).2,3 It also is an antagonist at histamine, muscarinic acetylcholine, α1-adrenergic, and dopamine receptors (Kds = 31, 37, 38, and 190 nM for H1, M1, α1, and D2, respectively).4

    WARNING This product is not for human or veterinary use.

    Technical Information
    Formal Name
    3-chloro-10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine, monohydrochloride
    CAS Number
    17321-77-6
    Molecular Formula
    C19H23ClN2 • HCl
    Formula Weight
    351.3
    Purity
    ≥98%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility
    • DMF: 3 mg/ml
    • DMSO: 10 mg/ml
    • Ethanol: 10 mg/ml
    • PBS (pH 7.2): 0.5 mg/ml
    SMILES
    ClC1=CC2=C(C=C1)CCC3=C(C=CC=C3)N2CCCN(C)C.Cl
    InChi Code
    InChI=1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
    InChi Key
    WIMWMKZEIBHDTH-UHFFFAOYSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years