This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG.

Cannabidiol (CBD) is one of the important cannabinoids found in plants of the Cannabaceae family known for its non-psychoactive properties. It forms upon the decarboxylation of its precursor cannabidiolic acid in the presence of light or heat. It shows various therapeutic properties, such as antioxidative, anti-inflammatory, antimicrobial, neuroprotective, anxiolytic, and anticonvulsant.

This primary reference standard can also be used as follows:

• Determination of four cannabinoids from an oil matrix using reversed-phase high-performance liquid chromatography (RP-HPLC) combined with a diode array detector (DAD)
• Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) based technique to measure cannabidiol, ∆9-tetrahydrocannabinol, and its metabolites in whole blood samples obtained from rats administered with high doses of cannabidiol
• Simultaneous determination of cannabidiol and tetrahydrocannabinol in different hemp oil-containing products using isocratic RP-HPLC coupled with UV detection
• Multi-analysis of hair samples for Δ9-tetrahydrocannabinol, cannabinol, and cannabidiol by liquid-liquid extraction (LLE) followed by gas chromatography-mass spectrometry based quantification
• Ultrasound-assisted extraction of cannabidiol from three different commercial topical products followed by GC-MS based determination

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