c-di-AMP sodium salt (HPLC)

SKU:
SML1231-1UMO
  • $216.00

    • Description

    c-di-AMP sodium salt ≥98% (HPLC)

    Synonym: 3′,5′-Cyclic diadenylic acid sodium salt, Adenylyl-(3′5′)-3′-adenylic acid, cyclic nucleotide sodium salt, Cyclic di-3′,5′-adenylate sodium salt, Cyclic diadenylate monophosphate sodium salt, Cyclic diadenylate sodium salt, Cyclic-di-AMP sodium salt

    • CAS Number 54447-84-6 (free acid)

       

    • Empirical Formula (Hill Notation) C20H24N10O12P2 · xNa+

       

    • Molecular Weight 658.41 (free acid basis)

       

    •  PubChem Substance ID 329825734

       

    •  NACRES NA.77

    Properties

    Related Categories A-AM, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
    Cyclic Nucleotide Metabolism, Cyclic Nucleotides and Analogs, G Proteins and Cyclic Nucleotides, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics
    Quality Level 100
    description contains 1μmol of powder (approx. 0.7mg)
    assay ≥98% (HPLC)
    form powder
    color white to beige
    storage temp. −20°C
    SMILES string NC1=NC=NC2=C1N=CN2[C@H](O3)[C@H](O)[C@H](OP(OC[C@@H]4[C@@H](O5)[C@@H](O)[C@H](N6C=NC7=C6N=CN=C7N)O4)(O)=O)[C@H]3COP5(O)=O.C

    Biochem/physiol Actions

    It has a role in various signaling pathways. In Gram-positive bacteria, it influences cell growth and survival and modulates virulence. c-di-AMP is formed by diadenylate cyclases (DACs), which are cyclase domain-containing proteins.[1]

    c-di-AMP is a bacterial secondary messenger. c-di-AMP acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.

    Preparation Note

    c-di-AMP is soluble in water (≥ 16 mM, limits have not been determined).

    Safety Information

    RIDADR 
    NONH for all modes of transport
    WGK Germany 
    WGK 3
    Flash Point(F) 
    Not applicable
    Flash Point(C) 
    Not applicable