Borneol, 500MG

SKU:
CAY-23467-500MG
  • $57.00

    • Description

    (+)-Borneol, 500MG

    (+)-Borneol is a bicyclic monoterpene and a stereoisomer of (–)-borneol (Item No. 23468) that has been found in various plants, including S. tomentosa, and has diverse biological activities including analgesic, neuroprotective, antioxidant, and antimicrobial properties.1,2,3,4 (+)-Borneol is a positive allosteric modulator of α1β2γ2L subunit-containing GABAA receptors (EC50 = 248 μM for human recombinant receptors).1 It dose-dependently increases the paw withdrawal threshold following segmental spinal nerve ligation surgery or intraplantar injection of complete Freund's adjuvant (CFA) in mouse paw.2 (+)-Borneol (100 μM) inhibits increases in reactive oxygen species (ROS) levels and cytotoxicity in SH-SY5Y neuroblastoma cells incubated with amyloid-β (1-42) (Aβ42; Item No. 20574).3 It also inhibits the growth of Gram-positive and Gram-negative bacteria in vitro, including E. coli, S. aureus, P. aeruginosa, P. vulgaris, and S. typhimurium (MICs = 125-250 μg/mL).4 Formulations containing (+)-borneol have been used as fragrance ingredients.

    WARNING This product is not for human or veterinary use.

    Formal Name
    (1R,2S,4R)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-ol
    CAS Number
    464-43-7
    Synonyms
    • D-Borneol
    • (1R)-(+)-Borneol
    • (+)-endo-Borneol
    Molecular Formula
    C10H18O
    Formula Weight
    154.3
    Purity
    ≥95%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility
    • DMF: 25 mg/ml
    • DMF:PBS(pH7.2) (1:2): 0.33 mg/ml
    • DMSO: 16 mg/ml
    • Ethanol: 16 mg/ml
    SMILES
    C[C@]1(C2(C)C)CC[C@@H]2C[C@@H]1O
    InChi Code
    InChI=1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1
    InChi Key
    DTGKSKDOIYIVQL-WEDXCCLWSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years