Biotin

SKU:
PHR1233-1G
  • $126.00

    • Description

    Biotin

    Pharmaceutical Secondary Standard; Certified Reference Material

    Synonym(s):
    D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H
    Empirical Formula (Hill Notation):
    C10H16N2O3S
    CAS Number:
    58-85-5
    Molecular Weight:
    244.31
    Beilstein:
    86838
    EC Number:
    200-399-3
    MDL number:
    MFCD00005541
    PubChem Substance ID:
    329823238
    NACRES:
    NA.24

    PROPERTIES

    grade

    certified reference material
    pharmaceutical secondary standard

    Quality Level

    300

    Agency

    traceable to Ph. Eur. B1116000
    traceable to USP 1071508

    API family

    biotin

    CofA

    current certificate can be downloaded

    technique(s)

    HPLC: suitable
    gas chromatography (GC): suitable

    mp

    231-233 °C (lit.)

    application(s)

    pharmaceutical (small molecule)

    format

    neat

    storage temp.

    2-30°C

    SMILES string

    [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

    InChI

    1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

    InChI key

    YBJHBAHKTGYVGT-ZKWXMUAHSA-N

    General description

    Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
    Biotin is a water-soluble vitamin, essential for amino acids and carbohydrates metabolism. It is involved in de novo synthesis of purine nucleotides and plays a role in gene expression and DNA replication.[1]

    Application

    Biotin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical preparations using a bio-sensing system[2] and chromatography techniques.[1][3]
    These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

    Analysis Note

    These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

    Other Notes

    This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

    Footnote

    To see an example of a Certificate of Analysis for this material enter LRAC0265 in the slot below. This is an example certificate only and may not be the lot that you receive.

    SAFETY INFORMATION

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 1

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable