4-Quinolone-3-Carboxamide Furan CB2 Agonist, 1mg, Item No. 11094

SKU:
CAY-11094-1mg
  • $44.00

    • Description

    4-Quinolone-3-Carboxamide Furan CB2 Agonist, 1mg, Item No. 11094

    Product Description

    Agonists of the peripheral cannabinoid (CB) receptor CB2 may have antinociceptive and anti-inflammatory effects, as well as prevent osteoporosis. 4-Quinolone-3-carboxamide Furan CB2 Agonist is a high-affinity ligand of CB2 (Ki = 8.5 nM) with little affinity for CB1 (Ki >10,000 nM). This compound demonstrates antinociceptive efficacy in the mouse formalin test at 1 mg/kg, an action which is blocked by a CB2-selective antagonist, AM630 (Item No. 10006974).

    WARNING This product is not for human or veterinary use.

    Technical Information
    Formal Name
    6-(2-furanyl)-1,4-dihydro-8-methoxy-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-3-quinolinecarboxamide
    CAS Number
    1314230-75-5
    Synonyms
    • 4Q3C CB2 Agonist
    Molecular Formula
    C30H36N2O4
    Formula Weight
    488.6
    Purity
    ≥98%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility
    • DMF: 3 mg/ml
    • DMSO: 3 mg/ml
    • Ethanol: 30 mg/ml
    • Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
    λmax
    220, 283, 339 nm
    SMILES
    O=C(C1=CN(CCCCC)C2=C(C=C(C3=CC=CO3)C=C2OC)C1=O)N[C@@]45CC6C[C@H](C5)C[C@H](C4)C6
    InChi Code
    InChI=1S/C30H36N2O4/c1-3-4-5-8-32-18-24(29(34)31-30-15-19-10-20(16-30)12-21(11-19)17-30)28(33)23-13-22(25-7-6-9-36-25)14-26(35-2)27(23)32/h6-7,9,13-14,18-21H,3-5,8,10-12,15-17H2,1-2H3,(H,31,34)/t19-,20+,21?,30?
    InChi Key
    NXZZNXUALWSJSD-AXUKMQSXSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 2 years
    Certificates of Analysis & Batch Specific Data

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