Description
Application
The solubility of lipophilic drugs increases linearly with the concentration of hydroxypropyl-β-cyclodextrin (HBC) in aqueous solution because of the complex between HBC and the drug. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility. Solutions may be lyophilized to produce freely soluble powders. Non-toxic in rabbits and mice.
(2-Hydroxypropyl)-β-cyclodextrin is a β-cyclodextrin derivative with enhanced water solubility. It is used as a solubilizer and stabilizer in pharmaceutical formulations. HP-β-CD also shows potent anticancer activity.
Legal Information
Cavasol is a registered trademark of Wacker Chemie AG
Specifications:
| Appearance (Color) | White to Off White |
| Appearance (Form) | Powder or Crystals |
| Loss on Drying | ≤ 7.0 % |
| Residue on Ignition | ≤ 2.5 % |
| Infrared Spectrum | CONFORMS TO STRUCTURE |
| Inpurities A, B and C | Polypropyeneglycol ≤ 5.0 % |
| Impurity E | Unsubstituted Cyclodextrine ≤ 1.0 % |
| Molar Substitution | Molar Substitution 0.6 - 0.9 |
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MilliporeSigma(2-Hydroxypropyl)-beta-cyclodextrin, 5G
SKU: 332607-5G
$61.80(2-Hydroxypropyl)-β-cyclodextrin, 5G average Mw ~1,460 Synonym(s): (2-Hydroxypropyl)-beta-cyclodextrin, HP-β-CD CAS Number: 128446-35-5 EC Number: 420-920-1 PubChem Substance... -
MilliporeSigma(2-Hydroxypropyl)-beta-cyclodextrin (500g)
SKU: 778907-500G
$719.00778907 Sigma-Aldrich (2-Hydroxypropyl)-β-cyclodextrin Produced by Wacker Chemie AG, Burghausen, Germany, Life Science Synonym: Cavasol® W7 HP CAS Number 128446-35-5 & -
MilliporeSigma(2-Hydroxypropyl)-Beta-cyclodextrin powder, 5G
SKU: H107-5G
$186.00(2-Hydroxypropyl)-β-cyclodextrin powder, 5G Synonym(s): 2-hydroxypropylether, Beta-cyclodextrin CAS Number: 128446-35-5 EC Number: 420-920-1 PubChem Substance ID: 24895425 NAC -
Benchmark ScientificAccuris Precision Balance, 500 grams, readability 0.001grams, 115V
SKU: W3200-500
$1,412.90Accuris Precision Balance, 500 grams, readability 0.001grams, 115V Accuris Precision balances quickly and accurately display sample measurements on a large, backlit LCD screen. Utilizing highly... -
Hardy DiagnosticsIodine, Grams, Stabilized, 8oz (250mL bottle), by Hardy Diagnostics
SKU: I008
$8.66Iodine, Grams, Stabilized, 8oz (250mL bottle), by Hardy Diagnostics A mordant used in the gram stain procedure. A stabilized, thicker iodine solution. Use with the intermediate decolorizer (Cat. no...
