Thiamine pyrophosphate, 25G

SKU:
C8754-25G
  • $300.00

    • Description

    Thiamine pyrophosphate ≥95%, 25G

    Synonym: Aneurinepyrophosphoric acid, Cocarboxylase, Thiamine pyrophosphate chloride

    • CAS Number 154-87-0

       

    • Empirical Formula (Hill Notation) C12H19ClN4O7P2S

       

    • Molecular Weight 460.77

       

    •  Beilstein/REAXYS Number 3875902

       

    •  EC Number 205-836-1

       

    •  MDL number MFCD00038740

       

    •  PubChem Substance ID 24893100

       

    •  NACRES NA.54

    Safety Information

    Personal Protective Equipment 
    Eyeshields, Gloves, type N95 (US)
    RIDADR 
    NONH for all modes of transport
    WGK Germany 
    WGK 3
    Flash Point(F) 
    Not applicable
    Flash Point(C) 
    Not applicable

    Application

    Thiamine pyrophosphate from Sigma has been used as a substrate to assay the enzymes in golgi lamellae isolated from rat tissue.[1]

    Thiamine pyrophosphate has been used:
    • for the preparation of chitosan nano-particles[3]
    • as a standard for vitamin B1 and its derivative in high-performance
    • liquid chromatography (HPLC) analysis[4]
    • immunofluorescence[5]

    Packaging

    1, 5, 25, 100 g in poly bottle

    Biochem/physiol Actions

    Thiamine pyrophosphate (TPP) is a coenzyme of transketolase, that catalyzes the cleavage of ribulose-5-phosphate. This reaction leads to the formation of D-glyceraldehyde-3-phosphate. It requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. TPP is capable of decarboxylating hydroxypyruvate in the presence of an ′acceptor aldehyde′.[2]