PSP, 5MG

SKU:
CAY-35589-5MG
  • $89.00
  • Description

    PSP, 5MG

    PSP is a two-photon fluorescent probe for hydrogen polysulfide (H2Sn), a reactive sulfur species (RSS) formed during ferroptosis.1 Upon reaction with H2Sn, the 2-fluoro-5-nitro-benzoate quenching group of PSP is removed, resulting in the release of a near-infrared emitting product. PSP is selective for H2Sn over a panel of reactive oxygen species (ROS), reactive nitrogen species (RNS), metal ions, and sulfur-containing ions. It has been used to detect H2Sn in live cells and tumor spheroids in vitro.

    WARNING This product is not for human or veterinary use.

    Technical Information
    Formal Name
    (E)-6-(2-(3-(dicyanomethylene)-5,5-dimethylcyclohex-1-en-1-yl)vinyl)naphthalen-2-yl 2-fluoro-5-nitrobenzoate
    Molecular Formula
    C30H22FN3O4
    Formula Weight
    507.5
    Purity
    ≥98%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility(Learn about Variance in Solubility)
    • DMF: 1 mg/ml
    λmax
    220, 251, 406 nm
    SMILES
    O=C(OC1=CC(C=CC(/C=C/C2=C/C(CC(C)(C)C2)=C(C#N)/C#N)=C3)=C3C=C1)C4=C(F)C=CC([N+]([O-])=O)=C4
    InChi Code
    InChI=1S/C30H22FN3O4/c1-30(2)15-20(12-23(16-30)24(17-32)18-33)4-3-19-5-6-22-13-26(9-7-21(22)11-19)38-29(35)27-14-25(34(36)37)8-10-28(27)31/h3-14H,15-16H2,1-2H3/b4-3+
    InChi Key
    XADDYEFXVWMUAY-ONEGZZNKSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Wet ice in continental US; may vary elsewhere
    Stability
    ≥ 2 years