Description
Ochratoxin A
Technical Information
Formal Name
N-[[(3R)-5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine
CAS Number
303-47-9
Synonyms
- NSC 201422
- NSC 221991
- OTA
Molecular Formula
C20H18ClNO6
Formula Weight
403.8
Purity
≥90%
Formulation
A crystalline solid
λmax
213, 331 nm
SMILES
O=C(O)C(NC(C1=CC(Cl)=C(C[C@@H](C)OC2=O)C2=C1O)=O)CC3=CC=CC=C3
InChi Code
InChI=1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1
InChi Key
RWQKHEORZBHNRI-BMIGLBTASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Product Description
Ochratoxin A (OTA) is a mycotoxin produced by A. ochraceus, A. carbonarius, and P. verrucosum that is commonly found as a food contaminant.1 The kidney is the main target organ for OTA toxicity where it has been reported to trigger nephropathy and induce renal adenomas.2 Topical OTA exposure (80 μg/mouse) also has skin tumor initiating properties which have been linked to oxidative stress, alterations in Nrf2 and MAPK signaling, and DNA damage.3 A tolerable weekly intake of 100 ng/kg body weight per day has been set by the joint FAO/WHO Expert Committee on Food Additives.2
WARNING This product is not for human or veterinary use.