Description
Nalidixic acid
≥98%
Synonym(s):
1,4-Dihydro-1-ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid, 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
Empirical Formula (Hill Notation):
C12H12N2O3
CAS Number:
389-08-2
Molecular Weight:
232.24
Beilstein/REAXYS Number:
750515
EC Number:
206-864-7
MDL number:
MFCD00006884
PubChem Substance ID:
24897864
NACRES:
NA.77
PROPERTIES
biological source
synthetic
Quality Level
200
assay
≥98%
form
powder
mp
227-229 °C (lit.)
solubility
chloroform: 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mode of action
DNA synthesis | interferes
enzyme | inhibits
SMILES string
CCN1C=C(C(O)=O)C(=O)c2ccc(C)nc12
InChI
1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17)
InChI key
MHWLWQUZZRMNGJ-UHFFFAOYSA-N
DESCRIPTION
General description
Chemical structure: quinolone
Application
Used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependen)t DNA supercoiling, and chromosome fragmentation.
SAFETY INFORMATION
signalword
Warning
hcodes
H302 - H351
pcodes
P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves