Description
MilliporeSigma Dimethyl sulfoxide (DMSO) (1L)
for headspace gas chromatography SupraSolv
Synonym(s):
Methanesulfinylmethane, Methyl sulfoxide, Dimethyl(oxido)sulfur, DMSO, DMSO
Linear Formula:
(CH3)2SO
CAS Number:
67-68-5
Molecular Weight:
78.13
Beilstein:
506008
MDL number:
MFCD00002089
EC Index Number:
200-664-3
PROPERTIES
Quality Level
100
Agency
according to Ph. Eur.
according to USP
vapor density
2.7 (vs air)
vapor pressure
0.42 mmHg ( 20 °C)
product line
SupraSolv®
assay
≥99.8% (GC)
form
liquid
autoignition temp.
573 °F
potency
28300 mg/kg LD50, oral (Rat)
40000 mg/kg LD50, skin (Rat)
expl. lim.
42 %, 63 °F
technique(s)
GC-HS: suitable
impurities
≤0.05% Water
evapn. residue
≤3.0 mg/L
color
APHA: ≤10
refractive index
n20/D 1.479 (lit.)
kinematic viscosity
2.14 cSt
bp
189 °C (lit.)
mp
16-19 °C (lit.)
transition temp
flash point 87 °C
density
1.10 g/mL (lit.)
storage temp.
2-30°C
SMILES string
CS(C)=O
InChI
1S/C2H6OS/c1-4(2)3/h1-2H3
InChI key
IAZDPXIOMUYVGZ-UHFFFAOYSA-N
General description
SupraSolv solvents for headspace gas chromatography are developed particularly for the analysis of residual
solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv headspace solvents are tested for all
residual solvents defined by the ICH.
solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv headspace solvents are tested for all
residual solvents defined by the ICH.
Caution
Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.
Specifications
Saturation Concentration in Air: 8.0 g/m3 (20 °C)
Analysis Note
Purity (GC): ≥ 99.8 %
Identity (IR): conforms
Evaporation residue: ≤ 3.0 mg/l
Water: ≤ 0.05 %
Color: ≤ 10 Hazen
GC/HS (Every residual solvent of class 1acc. ICH): ≤ 1 µg/g
GC/HS (Every residual solvent of class 2acc. ICH): ≤ 10 µg/g
GC/HS (Every residual solvent of class 3acc. ICH): ≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1,2 and 3 according to Ph Eur and USP.
Formic acid, acetic acid, dimethylacetamide and cumene are not detected.
Identity (IR): conforms
Evaporation residue: ≤ 3.0 mg/l
Water: ≤ 0.05 %
Color: ≤ 10 Hazen
GC/HS (Every residual solvent of class 1acc. ICH): ≤ 1 µg/g
GC/HS (Every residual solvent of class 2acc. ICH): ≤ 10 µg/g
GC/HS (Every residual solvent of class 3acc. ICH): ≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1,2 and 3 according to Ph Eur and USP.
Formic acid, acetic acid, dimethylacetamide and cumene are not detected.
Legal Information
SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
188.6 °F - closed cup
Flash Point(C)
87 °C - closed cup