Luteolin 7-O-Glucuronide, 1mg

SKU:
CAY-33188-1MG
  • $62.00
  • Description

    Product Description

    Luteolin 7-O-glucuronide is a flavonoid that has been found in S. chloroleuca and A. pilosa, and has diverse biological activities, including antioxidant, enzyme inhibitory, and anti-inflammatory properties. It scavenges DPPH radicals in a cell-free assay (IC50 = 80.6 μM). Luteolin 7-O-Glucuronide inhibits porcine α-amylase and yeast α-glucosidase in vitro (IC50s = 61.5 and 14.7 μM, respectively). It also inhibits rat aldose reductase in vitro (IC50 = 0.7 μM) and sorbitol accumulation in isolated rat lens by 91.8% when used at a concentration of 5 μg/ml. Luteolin 7-O-glucuronide inhibits LPS-induced cytokine release from RAW 264.7 macrophages in a dose-dependent manner.

    WARNING This product is not for human or veterinary use.

    Technical Information
    Formal Name
    2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-1-benzopyran-7-yl, β-D-glucopyranosiduronic acid
    CAS Number
    29741-10-4
    Synonyms
    • Luteolin-7-O-β-D-glucuronide
    Molecular Formula
    C21H18O12
    Formula Weight
    462.4
    Purity
    ≥98%
    Formulation
    A solid
    Solubility
    • DMSO: slightly soluble
    • Methanol: slightly soluble
    λmax
    256, 353 nm
    SMILES
    O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O)C=C2OC(C4=CC(O)=C(C=C4)O)=C1
    InChi Code
    InChI=1S/C21H18O12/c22-9-2-1-7(3-10(9)23)13-6-12(25)15-11(24)4-8(5-14(15)32-13)31-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-24,26-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
    InChi Key
    VSUOKLTVXQRUSG-ZFORQUDYSA-N
    Origin
    Plant/Lactuca sativa
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years