Description
Product Description
Luteolin 7-O-glucuronide is a flavonoid that has been found in S. chloroleuca and A. pilosa, and has diverse biological activities, including antioxidant, enzyme inhibitory, and anti-inflammatory properties. It scavenges DPPH radicals in a cell-free assay (IC50 = 80.6 μM). Luteolin 7-O-Glucuronide inhibits porcine α-amylase and yeast α-glucosidase in vitro (IC50s = 61.5 and 14.7 μM, respectively). It also inhibits rat aldose reductase in vitro (IC50 = 0.7 μM) and sorbitol accumulation in isolated rat lens by 91.8% when used at a concentration of 5 μg/ml. Luteolin 7-O-glucuronide inhibits LPS-induced cytokine release from RAW 264.7 macrophages in a dose-dependent manner.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-1-benzopyran-7-yl, β-D-glucopyranosiduronic acid
CAS Number
29741-10-4
Synonyms
- Luteolin-7-O-β-D-glucuronide
Molecular Formula
C21H18O12
Formula Weight
462.4
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: slightly soluble
- Methanol: slightly soluble
λmax
256, 353 nm
SMILES
O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O)C=C2OC(C4=CC(O)=C(C=C4)O)=C1
InChi Code
InChI=1S/C21H18O12/c22-9-2-1-7(3-10(9)23)13-6-12(25)15-11(24)4-8(5-14(15)32-13)31-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-24,26-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
InChi Key
VSUOKLTVXQRUSG-ZFORQUDYSA-N
Origin
Plant/Lactuca sativa
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years