MilliporeSigma
L-Thyroxine (T4) solution 100 ug/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant
- SKU:
- T-073-1ML
On Sale
Description
L-Thyroxine (T4) solution 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant
Synonym(s):
3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine, L-Thyroxine, 3,3′,5,5″-Tetraiodo-L-thyronine, T4
Linear Formula:
HOC6H2(I)2OC6H2(I)2CH2CH(NH2)CO2H
CAS Number:
51-48-9
Molecular Weight:
776.87
Beilstein/REAXYS Number:
2228515
MDL number:
MFCD00002595
PubChem Substance ID:
329826617
NACRES:
NA.24
Quality Level
300
grade
certified reference material
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in methanol with 0.1N NH3
mp
223 °C (dec.) (lit.)
Featured Industry
Forensics and Toxicology
format
single component solution
storage temp.
−20°C
SMILES string
N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O
InChI
1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
InChI key
XUIIKFGFIJCVMT-LBPRGKRZSA-N
Gene Information
human ... THRA(7067) , THRB(7068)
Thyroxine or T4 is a thyroid hormone responsible for regulation of the body′s basal metabolic rate and essential for growth, development and heart and nervous system function. Free and total T4 serum levels are measured by LC-MS/MS for determination of hyper- or hypothyroidism as well as for monitoring treatment with synthetic thyroid hormones. This Certified Spiking Solution® is suitable for use in LC-MS/MS testing methods as starting materials in preparation of linearity standards, calibrators, and controls.
Biochem/physiol Actions
L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis.
Legal Information
CERILLIANT is a registered trademark of Cerilliant Corporation
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation
Pictograms
GHS02,GHS06,GHS08
Signal Word
Danger
Hazard Statements
H225 - H301 + H311 + H331 - H370
Precautionary Statements
P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
Target Organs
Eyes
RIDADR
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany
WGK 1
Flash Point(F)
49.5 °F - closed cup
Flash Point(C)
9.7 °C - closed cup