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L-Cysteine from non-animal source, BioReagent, suitable for cell culture, (25g)

SKU:
C7352-25G
  • $71.60

    • Description

    C7352 Sigma-Aldrich

    L-Cysteine

    from non-animal source, BioReagent, suitable for cell culture, ≥98%

    Synonym: (R)-2-Amino-3-mercaptopropionic acid

    • CAS Number 52-90-4

       

    • Linear Formula HSCH2CH(NH2)CO2H

       

    • Molecular Weight 121.16

       

    •  Beilstein/REAXYS Number 1721408

       

    •  EC Number 200-158-2

       

    •  MDL number MFCD00064306

       

    •  eCl@ss 32160406

       

    •  PubChem Substance ID 24892959

       

    •  NACRES NA.75

    Description

    General description

    L-Cysteine is one of the sulfur containing proteinogenic amino acid incorporated into proteins as directed by the genetic code.[2] The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of β bonds that modulate the secondary and ternary structure of proteins. L-Cysteine is an essential precursor for inorganic sulfates, coenzyme A.[2] Cysteine is an essential and limiting for the formation of glutathione, an important antioxidant, within the cell. Mammalian liver can synthesize L-cysteine and is a semi-essential amino acid. L-cysteine prevents oxidation of nerve cells, aids in maintaining the stability and rigidity of connective tissues. L-cysteine speeds up the healing process of the body and reduces inflammatory reactions. L-cysteine protects testis partially against acrylamide induced toxicity.[2] L-cysteine can prevent DNA damage during cryopreservation and preserves semen quality.[3]

    L-Cysteine is a proteinogenic amino acid incorporated into proteins as directed by the genetic code. The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of β bonds that modulate the secondary and ternary structure of proteins. Cysteine is essential and limiting for the formation of glutathione, an important antioxidant, within the cell.

    Application

    L-Cysteine has been used:
    • as a media supplement in Trypticase-Yeast Extract-Iron-Serum (TYI-S-33) media for the culture of Giardia lamblia,[1] to make enzyme solution in Dulbecco′s modified Eagles medium (DMEM) to establish hippocampus culture[4]
    • to test its protective effect on acrylamide induced toxicity in testis[2]
    • in the preparation of tris acetic acid extender solution for cryopreservation of semen[3]
    • as an additive to make papain digestion solution[5]

    Packaging

    1 kg in poly bottle

    10 mg in glass bottle

    25, 100 g in poly bottle

    Biochem/physiol Actions

    NMDA glutamatergic receptor agonist.

     

    Properties

    Related Categories Acacia, Amino Acid, Amino Acids, Amino Acids & Derivatives, Amino Acids & Vitamins,
    More...
    Quality Level   200
    biological source   non-animal source
    product line   BioReagent
    assay   ≥98%
    form   crystalline powder
    application(s)   cell culture | mammalian: suitable
    impurities   endotoxin, tested
    color   white
    mp   240 °C (dec.) (lit.)
    solubility   H2O: 25 mg/mL
    SMILES string   N[C@@H](CS)C(O)=O
    InChI   1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
    InChI key   XUJNEKJLAYXESH-REOHCLBHSA-N