Ganoderol B, Item No. 34324, 1mg

SKU:
CAY-34324-1mg
  • $81.00

    • Description

    Ganoderol B

    Item No. 34324

    Technical Information
    Formal Name
    lanosta-7,9(11),24E-triene-3β,26-diol
    CAS Number
    104700-96-1
    Synonyms
    • Ganodermadiol
    • (+)-Ganoderol B
    Molecular Formula
    C30H48O2
    Formula Weight
    440.7
    Purity
    ≥95%
    Formulation
    A solid
    Solubility
    • DMSO: soluble
    SMILES
    C[C@]12C3=CC[C@](C(C)([C@H](CC4)O)C)([H])[C@@]4(C)C3=CC[C@@]1([C@]([C@@H](CC/C=C(C)/CO)C)([H])CC2)C
    InChi Code
    InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1
    InChi Key
    AOXXVRDKZLRGTJ-AZIDVCJLSA-N
    Origin
    Fungi/Ganoderma lucidum
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years
    Product Description

    Ganoderol B is a triterpenoid that has been found in G. lucidum and has diverse biological activities.1,2,3,4,5 It inhibits angiotensin-converting enzyme (ACE) and α-glucosidase (IC50s = 220 and 119.8 µM, respectively).1,2 Ganoderol B is cytotoxic to HGC-27 gastric, HeLa cervical, and A549 lung cancer cells (IC50s = 16.15, 12.64, and 9.77 µM, respectively).3 It prevents herpes simplex virus 1 (HSV-1) infection in Vero cells (EC50 = 68 µM).4 Ganoderol B (0.001 and 0.1 mg/kg) reduces testosterone-induced increases in ventral prostate weight in castrated rats.5

    WARNING This product is not for human or veterinary use.