Description
Ganoderic Acid B
Ganoderic acid B is a triterpenoid that has been found in G. lucidum and has diverse biological activities.1,2,3 It inhibits HIV-1 protease with an IC50 value of 0.17 mM.1 Ganoderic acid B is cytotoxic to HepG2 and Caco-2 cells (IC50s = 0.65 and 0.36 mg/ml, respectively).2 It inhibits acetic acid-induced writhing in mice by 48.3% when administered at a dose of 5 mg/kg.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3β,7β,25R)- 3,7-dihydroxy- 11,15,23- trioxo-lanost- 8-en-26-oic acid
CAS Number
81907-61-1
Molecular Formula
C30H44O7
Formula Weight
516.7
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: Soluble
λmax
255 mn
SMILES
O[C@H]1CC[C@@]2(C)[C@](C[C@H](O)C([C@@](C(C[C@]3([H])[C@H](C)CC(C[C@@H](C)C(O)=O)=O)=O)(C)[C@]3(C)C4)=C2C4=O)([H])C1(C)C
InChi Code
InChI=1S/C30H44O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21-22,32,34H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21+,22+,28+,29-,30+/m1/s1
InChi Key
LWPLEHFGBRFRKI-NBCWKOIPSA-N
Origin
Fungi/Ganoderma lucidum
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years