Diisobutylaluminum hydride solution, 700G

SKU:
192724-700G
  • $368.00

    • Description

    Diisobutylaluminum hydride solution, 700G

    25 wt. % in toluene

    Synonym(s):
    DIBAL, DIBAL-H
    Linear Formula:
    [(CH3)2CHCH2]2AlH
    CAS Number:
    1191-15-7
    Molecular Weight:
    142.22
    Beilstein:
    4123663
    MDL number:
    MFCD00008928
    PubChem Substance ID:
    24851561
    NACRES:
    NA.22

    PROPERTIES

    form

    liquid

    Quality Level

    200

    reaction suitability

    reagent type: reductant

    concentration

    25 wt. % in toluene

    density

    0.846 g/mL at 25 °C

    SMILES string

    CC(C)C[AlH]CC(C)C

    InChI

    1S/2C4H9.Al.H/c2*1-4(2)3;;/h2*4H,1H2,2-3H3;;

    InChI key

    AZWXAPCAJCYGIA-UHFFFAOYSA-N

    DESCRIPTION

    General description

    Diisobutylaluminum hydride reducing agent is commonly used for the reduction of an ester to aldehyde.[1]

    Application

    Diisobutylaluminum hydride solution (25 wt. % in toluene) has been used for the reduction of imides:[2]
    • N

    • -(cis-2-Vinylcyclohexyl)succinimide to 1-(cis-2-vinylcyclohexyl)-5-hydroxy-2-pyrrolidinone
    • N-(But-4-en-1-y1)-2(E)-(carbethoxymethylidene)-5-oxo-pyrrolidine to N-(but-4-en-1-yl)- 2(E)-(carbethoxymethylidene)-5-hydroxypyrrolidine
    • N-(Hept-1-en-4-y1)-2(E)-(carbethoxymethylidene)-5-oxo-pyrrolidine to N-(hept-1-en-4-y1)-2(E)-(carbethoxymethylidene)-5-hydroxypyrrolidine
    • N-(cis-2-Vinylcyclohexyl)-2-(carbethoxymethylidene)-5-oxopyrrolidine to rel-(3aR,SS,5aS,SaR)-1( E)-(carbethoxymethylidene)-5-(formyloxy)dodecahydropyrrolo[1,2-a]quinoline
    Used in Pd-catalyzed reductive debromination of secondary alkyl bromides. O-Debenzylation and ring opening of perbenzylated furanosides. Convenient in situ generation of HZrCp2Cl from ZrCp2Cl2 and DIBAL-H.

    Packaging

    4×25, 100, 700 g in Sure/Seal™
    7, 15 kg in Kilo-Lab™
    The 25 g Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.
    View returnable container options.

    Legal Information

    Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

    SAFETY INFORMATION

    Signal Word

    Danger

    Hazard Statements

    H225 - H250 - H260 - H304 - H314 - H336 - H361d - H373 - H412

    Precautionary Statements

    P210 - P231 + P232 - P280 - P301 + P310 + P331 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310 - P370 + P378

    Hazard Classifications

    Aquatic Chronic 3 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 - STOT SE 3 - Water-react 1

    Target Organs

    Central nervous system

    Supplementary Hazards

    EUH014

    Storage Class Code

    4.2 - Pyrophoric and self-heating hazardous materials

    WGK

    WGK 3

    Flash Point(F)

    39.2 °F - closed cup

    Flash Point(C)

    4 °C - closed cup

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves