Diisobutylaluminum hydride solution, 1.0 M in THF, 100mL

SKU:
214981-100ML
  • $76.30

    • Description

    Diisobutylaluminum hydride solution, 1.0 M in THF, 100mL

    Synonym(s):
    DIBAL, DIBAL-H
    Linear Formula:
    [(CH3)2CHCH2]2AlH
    CAS Number:
    1191-15-7
    Molecular Weight:
    142.22
    Beilstein:
    4123663
    MDL number:
    MFCD00008928
    eCl@ss:
    38120609
    PubChem Substance ID:
    24852859
    NACRES:
    NA.22

    form

    liquid

    Quality Level

    200

    reaction suitability

    reagent type: reductant

    concentration

    1.0 M in THF

    bp

    65 °C

    density

    0.866 g/mL at 25 °C

    storage temp.

    2-8°C

    SMILES string

    CC(C)C[AlH]CC(C)C

    InChI

    1S/2C4H9.Al.H/c2*1-4(2)3;;/h2*4H,1H2,2-3H3;;

    InChI key

    AZWXAPCAJCYGIA-UHFFFAOYSA-N

    Diisobutylaluminum hydride solution (1M in THF) is a powerful reducing agent. It can be used in the following reactions:
    • Synthesis of trans-alkene isosteres of protected dipeptides.
    • To generate bis(1,5-cyclooctadiene)nickel(0) (Ni(cod)2) in situ, which can catalyze theconjugate addition of ethenyltributyltinto 2-propenal to form tert-butyldimethyl[((E)-1,4pentadienyl)oxy]silane.
    • Reduction of the arylpropiolate esters to give the corresponding propargyl alcohol.
    Used in Pd-catalyzed reductive debromination of secondary alkyl bromides. O-Debenzylation and ring opening of perbenzylated furanosides. Convenient in situ generation of HZrCp2Cl from ZrCp2Cl2 and DIBAL-H.

    Packaging

    100, 800 mL in Sure/Seal™
    18 L in Kilo-Lab™