Astaxanthin, (HPLC), from Blakeslea trispora, 50mg

Astaxanthin ≥97% (HPLC), from Blakeslea trispora, 50mg

Synonym: (3S,3′S)-3,3′-Dihydroxy-β,β-Carotene-4,4′-dione, 3,3′-Dihydroxy-β-carotene-4,4′-dione, trans-Astaxanthin

• CAS Number 472-61-7

   

• Empirical Formula (Hill Notation) C₄₀H₅₂O₄

   

• Molecular Weight 596.84

Properties

General description

Astaxanthin (AST) is a red dietary carotenoid. It is mainly found in aquatic animals and microalgae, such as Haematococcus pluvialis and Chlorella zofingiensis.^[3]

Application

Astaxanthin has been used:
• as an antioxidant to study its effect on Brachionus manjavacas (Rotifera) population growth^[1]
• to study its effects on the treatment of diabetic retinopathy.^[1][2]
• to investigate its role in restoring the expression of Nrf2 (nuclear factor erythroid 2 p45-related factor 2) and glutathione S-transferase P1 (GSTP1) through epigenetic modification in human prostate LNCaP cells.^[3]

Packaging

50 mg in glass bottle

Biochem/physiol Actions

In vivo and in vitro studies propose that astaxanthin (AST) possesses health-promoting activities, signifying its potential use in the prevention of various diseases, such as cancers and Parkinson’s disease.^[3] Due to its bright red colour, AST has been used as a food colorant in animal feeds.^[2]

Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity. Astaxanthin protects against oxidative stress, inhibiting NF-KB, suppressing pro-inflammatory genes and suppressing production of pro-inflammatory compounds nitric oxide, prostaglandin E2, TNF-α, and interleukin-1β. Astaxanthin′s protection of cells from oxidative stress generated by TNF-α and palmitate has been shown to ameliorate insulin resistance. Astaxanthin has also been shown to be an inhibitor of PPARγ.

Safety Information