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Acetone, for liquid chromatography LiChrosolv, 2.5L

SKU:
1000202500
  • $187.00

    • Description

    Acetone, for liquid chromatography LiChrosolv®

    Synonym(s):
    Dimethyl ketone, Propanone, 2-Propanone
    Linear Formula:
    CH3COCH3
    CAS Number:
    67-64-1
    Molecular Weight:
    58.08
    Beilstein/REAXYS Number:
    635680
    MDL number:
    MFCD00008765
    EC Index Number:
    200-662-2

    PROPERTIES

    grade

    HPLC grade
    isocratic

    Quality Level

    100

    vapor density

    2 (vs air)

    vapor pressure

    184 mmHg ( 20 °C)

    product line

    LiChrosolv®

    assay

    ≥99.8% (GC)

    form

    liquid

    autoignition temp.

    465 °C (DIN 51794)

    potency

    5800 mg/kg LD50, oral (Rat)
    20000 mg/kg LD50, skin (Rabbit)

    expl. lim.

    13.2 %

    technique(s)

    HPLC: suitable

    impurities

    ≤0.0002 meq/g Acidity
    ≤0.0002 meq/g Alkalinity
    ≤0.05% Water

    evapn. residue

    ≤2.0 mg/L

    transmittance

    335 nm, ≥50%
    340 nm, ≥80%
    350 nm, ≥98%

    refractive index

    n20/D 1.359 (lit.)

    pH

    5-6 (20 °C, 395 g/L in H2O)

    capacity

    1000 g/kg water absorbing capacity

    bp

    56 °C/760 mmHg (lit.)

    mp

    −94 °C (lit.)

    transition temp

    flash point <-20 °C

    density

    0.791 g/mL at 25 °C (lit.)

    format

    neat

    storage temp.

    2-30°C

    SMILES string

    CC(C)=O

    InChI

    1S/C3H6O/c1-3(2)4/h1-2H3

    InChI key

    CSCPPACGZOOCGX-UHFFFAOYSA-N

    General description

    LiChrosolv® solvents show high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

    Application

    Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .
    Intended for HPLC and UHPLC-MS applications, either as an extraction solvent or as a mobile phase.
    Reported for use in LC–MS/MS investigations of:
    • blood plasma and serum samples fractionated on several chromatography sorbents[1][2]
    • peptides in animal biological samples[3]

    Features and Benefits

    • suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
    • specified quality in positive and negative in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)
    —ESI/APCI (+) < 2 ppb
    —ESI/APCI (-) < 10 ppb
    • lowest impurity profile: for interference-free baselines (test 2)
    • microfiltered through 0.2 μm filter (test 3) to provide:
    —a long lifespan to filters and mechanical parts of HPLC systems
    —reduced risk of column clogging

    • packed in borosilicate glass bottles for minimized metal ion contaminations
    • lowest levels of trace metal impurities for a minimum metal ion adduct formation
    —<5 ppb
    • lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)

    Preparation Note

    Product filtered through a 0.2 μm filter

    Other Notes

    Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

    Legal Information

    LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

    SAFETY INFORMATION

    pictograms

    GHS02,GHS07

    signalword

    Danger

    hcodes

    H225 - H319 - H336

    pcodes

    P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338

    Hazard Classifications

    Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

    target_organs

    Respiratory system

    supp_hazards

    EUH066

    Storage Class

    3 - Flammable liquids

    wgk_germany

    WGK 1

    flash_point_f

    1.4 °F - closed cup

    flash_point_c

    -17.0 °C - closed cup