(2-Hydroxypropyl)-beta-cyclodextrin (500g)

SKU:
778907-500G
  • $719.00

    • Description

    778907 Sigma-Aldrich

    (2-Hydroxypropyl)-β-cyclodextrin

    Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

    Synonym: Cavasol® W7 HP

    • CAS Number 128446-35-5

       

    •  EC Number 420-920-1

       

    •  NACRES NA.22

    Application

    The solubility of lipophilic drugs increases linearly with the concentration of hydroxypropyl-β-cyclodextrin (HBC) in aqueous solution because of the complex between HBC and the drug. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility. Solutions may be lyophilized to produce freely soluble powders. Non-toxic in rabbits and mice

    Legal Information

    Cavasol is a registered trademark of Wacker Chemie AG

    Specifications:

    Appearance (Color) White to Off White
    Appearance (Form) Powder or Crystals
    Remarks on GC Propylene glycol ≤ 0.5%
    Solubility (Color) Colorless
    Solubility (Turbidity) Clear
    Loss on Drying ≤ 10.0 %
    Infrared Spectrum Conforms to Structure
    Inpurities A (EP) identity confirmed
    Related Substances Related substances ≤ 0.1 % each
    Impurities A, B, and C Propyleneoxide ≤ 1.0 ppm
    Degree of Substitution Molar Substitution 0.59 - 0.73
    Heavy Metals ≤ 5 ppm
    Remark Related Substances, Sum ≤ 1.0 %
    Conductivity (20C) ≤ 200 uS/cm (100g/L)
    Remarks Betadex ≤ 1.0 %