(2-Hydroxypropyl)-beta-cyclodextrin 500 Grams

SKU:
778966-500G
  • $803.00
  • Description

    Application

    The solubility of lipophilic drugs increases linearly with the concentration of hydroxypropyl-β-cyclodextrin (HBC) in aqueous solution because of the complex between HBC and the drug. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility. Solutions may be lyophilized to produce freely soluble powders. Non-toxic in rabbits and mice.

    (2-Hydroxypropyl)-β-cyclodextrin is a β-cyclodextrin derivative with enhanced water solubility. It is used as a solubilizer and stabilizer in pharmaceutical formulations. HP-β-CD also shows potent anticancer activity.

    Legal Information

    Cavasol is a registered trademark of Wacker Chemie AG

    Specifications:

    Appearance (Color) White to Off White
    Appearance (Form) Powder or Crystals
    Loss on Drying ≤ 7.0 %
    Residue on Ignition ≤ 2.5 %
    Infrared Spectrum CONFORMS TO STRUCTURE
    Inpurities A, B and C Polypropyeneglycol ≤ 5.0 %
    Impurity E Unsubstituted Cyclodextrine ≤ 1.0 %
    Molar Substitution Molar Substitution 0.6 - 0.9