Wogonin, 5mg

SKU:
CAY-14248-5MG
  • $64.00

    • Description

    Product Description

    Wogonin is an O-methylated flavonoid isolated from the root of the traditional Chinese herb S. baicalensis with anti-inflammatory, antioxidant, and neuroprotective activities. At concentrations of 5-50 μM, wogonin inhibits inflammatory activation of cultured brain microglia by diminishing LPS-induced TNF-α, IL-1β, and nitric oxide production. Wogonin at 75 μM demonstrates tumor therapeutic potential inducing sub-G1 phase apoptosis through activation of caspase-3 activity in human osteocarcinoma cell lines.

    WARNING This product is not for human or veterinary use.

    Technical Information
    Formal Name
    5,7-dihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one
    CAS Number
    632-85-9
    Synonyms
    • BRN 0287152
    Molecular Formula
    C16H12O5
    Formula Weight
    284.3
    Purity
    ≥98%
    Formulation
    A crystalline solid
    Solubility
    • DMF: 20 mg/ml
    • DMSO: 20 mg/ml
    • DMSO:PBS (pH 7.2) (1:1): 0.1 mg/ml
    • Ethanol: 0.1 mg/ml
    λmax
    210, 275 nm
    SMILES
    O=C1C2=C(O)C=C(O)C(OC)=C2OC(C3=CC=CC=C3)=C1
    InChi Code
    InChI=1S/C16H12O5/c1-20-15-12(19)7-10(17)14-11(18)8-13(21-16(14)15)9-5-3-2-4-6-9/h2-8,17,19H,1H3
    InChi Key
    XLTFNNCXVBYBSX-UHFFFAOYSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years