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Urea, crystalline, EMPROVE, 25KG

SKU:
1084329029
  • $1,599.35

    • Description

    Urea, crystalline, EMPROVE® 

    API, Ph. Eur., BP, USP

    Synonym(s):
    Carbamide, Carbonyl diamide, Carbonyldiamine, Diaminomethanone, Carbonyldiamide
    Linear Formula:
    NH2CONH2
    CAS Number:
    57-13-6
    Molecular Weight:
    60.06
    Beilstein:
    635724
    MDL number:
    MFCD00008022
    EC Index Number:
    200-315-5

    PROPERTIES

    biological source

    synthetic

    Quality Level

    600

    grade

    GMO free
    GMP
    Halal
    Kosher

    Agency

    BP
    Ph. Eur.
    USP

    product line

    EMPROVE® API

    form

    crystalline

    impurities

    low in endotoxins

    mp

    132-135 °C (lit.)

    density

    1.335 g/mL at 25 °C (lit.)

    application(s)

    ophthalmics
    pharmaceutical
    semi-solid formulation

    foreign activity

    Aflatoxin free

    storage temp.

    2-25°C

    SMILES string

    NC(N)=O

    InChI

    1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

    InChI key

    XSQUKJJJFZCRTK-UHFFFAOYSA-N

    General description

    We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs.
    As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

    Application

    Urea as an active pharmaceutical ingedient is used mainly in dermatology for cremes and ointments and for ophthalmic applications. Urea crystalline Emprove® API is manufactured under ICH Q7. A CEP and an US-DMF is available.
    Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

    Packaging

    1.08432.0001 // 3x 1kg // PE bottle
    1.08432.1000 // 1kg // PE bottle
    1.08432.5000 // 5kg // PE bottle
    1.08432.9029 // 25 kg //Double PE bag

    Legal Information

    Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
    SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

    SAFETY INFORMATION

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 1

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable