Thiourea, 500g

SKU:
T8656-500G
  • $153.00

    • Description

    Thiourea, 500g

    ACS reagent, ≥99.0%

    Synonym(s):
    Sulfourea, Thiocarbamide
    Linear Formula:
    NH2CSNH2
    CAS Number:
    62-56-6
    Molecular Weight:
    76.12
    Beilstein/REAXYS Number:
    605327
    EC Number:
    200-543-5
    MDL number:
    MFCD00008067
    UNSPSC Code:
    12352100
    PubChem Substance ID:
    24900549
    NACRES:
    NA.21

    Properties

    grade

    ACS reagent

    Quality Level

    200

    assay

    ≥99.0%

    ign. residue

    ≤0.1% (as SO4)

    loss

    ≤0.5% loss on drying, 105°C, 2h

    mp

    170-176 °C (lit.)
    174-177 °C

    solubility

    H2O: passes test

    SMILES string

    NC(N)=S

    InChI

    1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

    InChI key

    UMGDCJDMYOKAJW-UHFFFAOYSA-N

    Gene Information

    mouse ... Ephx2(13850)

    Description

    General description

    Thiourea is an analogue of urea containing sulphur.[1]

    Application

    Thiourea has been used:
    • as a component of lysis buffer for liver tissue homogenization[2]
    • in 2-D sample buffer for two-dimensional in-gel protein tyrosine phosphatases (PTP) assay[3]
    • in rehydration buffer for protein extraction[4]
    Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

    Biochem/physiol Actions

    Thiourea is a free radical scavenger of the peroxide radical.[2] It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.[1]

    Safety Information

    signalword

    Warning

    hcodes

    H302 - H351 - H361fd - H411

    pcodes

    P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313

    Hazard Classifications

    Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

    Storage Class

    11 - Combustible Solids

    wgk_germany

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    ppe

    Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges