We will be closed Monday 01.20.2025 in
Observance of Martin Luther King, Jr. Day

tetrahydro-Harmine, 5mg

SKU:
CAY-14449-5MG
  • $46.00

    • Description

    tetrahydro-Harmine, 5mg

    Synonyms
    Synonyms
    • Leptaflorine
    • THH
    Technical Information
    Formal Name
    2,3,4,9-tetrahydro-7-methoxy-1-methyl-1H-pyrido[3,4-b]indole
    CAS Number
    17019-01-1
    Molecular Formula
    C13H16N2O
    Formula Weight
    216.3
    Purity
    ≥98%
    Formulation
    A crystalline solid
    Solubility
    • DMF: 1.5 mg/ml
    • DMSO: 2 mg/ml
    • Ethanol: 1.5 mg/ml
    • PBS (pH 7.2): 0.25 mg/ml
    λmax
    228, 271, 299 nm
    SMILES
    CC(NCC1)C2=C1C(C=CC(OC)=C3)=C3N2
    InChi Code
    InChI=1S/C13H16N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7-8,14-15H,5-6H2,1-2H3
    InChi Key
    ZXLDQJLIBNPEFJ-UHFFFAOYSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 2 years

    tetrahydro-Harmine (THH) is a fluorescent indole alkaloid extracted from B. caapi, a woody vine that is used to produce a psychoactive beverage, ayahuasca, which has been ritually ingested for medicoreligious purposes throughout South America since pre-Columbian times.1 THH inhibits monoamine oxidase (MAO)-A and MAO-B with much weaker potency (IC50s = 74 nM and >100 μM, respectively) compared to the companion harmala alkaloids also found in B. caapi: harmaline (Item No. 10995; IC50s = 2.5 nM and 25 μM, respectively) and harmine (Item No. 10010324; IC50s = 2 nM and 20 μM, respectively).2,3

    WARNING This product is not for human or veterinary use.