Tebuconazole-d9

SKU:
CAY-33287-5MG
  • $530.00
  • Description

    Tebuconazole-d9

    Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole (Item No. 24052) by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi.1 It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively.2 It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay.3 Tebuconazole (50 and 100 mg/kg per day) administered during gestation reduces testosterone levels and increases testicular levels of progesterone and 17α-hydroxyprogesterone in male rat fetuses.4 It has a feminizing effect on male pups and a virilizing effect on female pups. When administered to rats gestationally through postnatal day 42, tebuconazole (20 and 60 mg/kg per day) leads to cell death of pyramidal cells in the CA3-4 region of the hippocampus and layer V of the cortex concomitant with impairment in learning the platform location in the Morris water maze.5

    WARNING This product is not for human or veterinary use.

    This product is sold exclusively for research and analytical uses. It is formulated and packaged for use in controlled laboratory settings. Bulk sizes are not available for purchase.

    Technical Information
    Formal Name
    α-[2-(4-chlorophenyl)ethyl]-α-(1,1-dimethylethyl-d9)-1H-1,2,4-triazole-1-ethanol
    CAS Number
    1246818-83-6
    Molecular Formula
    C16H13ClD9N3O
    Formula Weight
    316.9
    Purity
    ≥99% deuterated forms (d1-d9)
    Formulation(Request formulation change)
    A solid
    Solubility
    • Acetonitrile: soluble
    • DMSO: soluble
    • Methanol: soluble
    SMILES
    ClC(C=C1)=CC=C1CCC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])(O)CN2C=NC=N2
    InChi Code
    InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3/i1D3,2D3,3D3
    InChi Key
    PXMNMQRDXWABCY-GQALSZNTSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years