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Taurocholic acid sodium salt hydrate, 1G

SKU:
T4009-1G
  • $59.60

    • Description

    Taurocholic acid sodium salt hydrate 

    ≥95% (HPLC)

    Synonym(s):
    2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide, Sodium taurocholate hydrate
    Empirical Formula (Hill Notation):
    C26H44NNaO7S · xH2O
    CAS Number:
    345909-26-4
    Molecular Weight:
    537.68 (anhydrous basis)
    EC Number:
    205-653-7
    MDL number:
    MFCD00150819
    PubChem Substance ID:
    24900186
    NACRES:
    NA.25

    PROPERTIES

    biological source

    synthetic (organic)

    Quality Level

    200

    description

    anionic

    assay

    ≥95% (HPLC)

    form

    powder

    mol wt

    micellar avg mol wt 2100

    aggregation number

    4

    CMC

    3-11 mM (20-25°C)

    functional group

    sulfonic acid

    shipped in

    ambient

    storage temp.

    room temp

    SMILES string

    [Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O

    InChI

    1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1

    InChI key

    RDAJAQDLEFHVNR-NEMAEHQESA-M

    DESCRIPTION

    General description

    Taurocholic acid sodium salt hydrate is a bile acid with detergent capabilities. [1]

    Application

    Taurocholic acid sodium salt hydrate has been used in a study to assess the adsorption of bile acids and salts to vegetable fibrous tissue. [2] It has also been used in a study to investigate a method for determination of conjugated and unconjugated bile salts in serum and jejunal fluid. [3]
    Anionic detergent used for protein solubilization.

    Packaging

    250 mg in poly bottle
    1, 5, 25, 100 g in poly bottle

    Biochem/physiol Actions

    Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.

    Preparation Note

    Synthesized from cholic acid

    SAFETY INFORMATION

    Storage Class Code

    13 - Non Combustible Solids

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves