Description
Squalene
≥98%, liquid
Synonym(s):
2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene
Linear Formula:
[(CH3)2C[=CHCH2CH2C(CH3)]2=CHCH2-]2
CAS Number:
111-02-4
Molecular Weight:
410.72
Beilstein:
1728919
EC Number:
203-826-1
MDL number:
MFCD00008912
PubChem Substance ID:
24899564
NACRES:
NA.25
PROPERTIES
Quality Level
100
Assay
≥98%
form
liquid
color
light yellow
refractive index
n20/D 1.494 (lit.)
bp
285 °C/25 mmHg (lit.)
mp
−75 °C (lit.)
density
0.858 g/mL at 25 °C (lit.)
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
SMILES string
CC(C)=CCCC(C)=CCCC(C)=CCC\C=C(/C)CCC=C(C)CCC=C(C)C
InChI
1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+
InChI key
YYGNTYWPHWGJRM-AAJYLUCBSA-N
DESCRIPTION
General description
Squalene is a hydrocarbon containing double bond commonly found in shark liver oil. It is also present in vegetable oils but to a lesser extent.[1]
Application
Squalene has been used:
- as a standard for lipid identification and quantification[2]
- in the isolation of macrophages for parasite incubation[3]
- as a standard for the quantification of squalene in squalene analysis of oil samples[4]
Biochem/physiol Actions
Squalene is a biosynthetic precursor to all steroids. It acts as a cytoprotective agent to normal cells exposed to carcinogens and antitumor agents. Squalene helps in equalizing the blood cholesterol levels. It increases the production of HDL (high density lipoprotein) and the excretion of LDL (low density lipoprotein). This helps in reducing the risk of heart disease and protects the less stable body fats from oxidation. It is also used in treating hypercholesterolemia. Squalene is known to improve the efficiency of cholesterol lowering drugs. It also serves as an antioxidant by preventing the effects of free radical. It protects skin from drying and other environmental conditions such as oxidation, ultraviolet rays and pollutants. Squalene is known to promote wound healing.[5]
SAFETY INFORMATION
Signal Word
Danger
Hazard Statements
H304
Precautionary Statements
P301 + P310 - P331 - P405 - P501
Hazard Classifications
Asp. Tox. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves